Last update
5/21/2026
Reviewed By
Reviewed By
Overview
SCIENTIFIC SCORE
Likely Ineffective
Based on 2 Researches
4.8
USERS' SCORE
Moderately Good
Based on 9 Reviews
7.9
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Coenzyme Q10 (CoQ10)
100 mg
**
Top Medical Research Studies
0
CoQ10 ineffective for mitochondrial sleep apnea
We examined a rare case of mitochondrial encephalomyopathy featuring multiple complications including sleep apnea, cerebellar ataxia, and peripheral neuropathy—a combination never before documented in medical literature. The patient received six months of coenzyme Q10 therapy to address the underlying mitochondrial dysfunction.
Unfortunately, the treatment proved ineffective. Neither the cerebellar ataxia nor the abnormal pyruvate metabolism improved with CoQ10 supplementation. While sleep apnea was identified as a significant prognostic factor in this mitochondrial disorder, the supplement failed to alleviate this serious breathing complication or other associated symptoms.
Unfortunately, the treatment proved ineffective. Neither the cerebellar ataxia nor the abnormal pyruvate metabolism improved with CoQ10 supplementation. While sleep apnea was identified as a significant prognostic factor in this mitochondrial disorder, the supplement failed to alleviate this serious breathing complication or other associated symptoms.
Read More
9.5
Coenzyme Q10 in sleep apnea study
We explored the impact of various treatments, including coenzyme Q10, on obstructive sleep apnea (OSA) in a patient with adult-onset Leigh disease. This condition often presents with severe neurological symptoms, complicating the patients’ overall health and quality of life.
An overnight sleep study revealed the presence of OSA, which had developed shortly before the neurological symptoms became apparent. Treatment included high doses of thiamine, coenzyme Q, L-carnitine, and vitamins C and E, along with effective management of OSA through continuous positive airway pressure (CPAP).
Following this combined approach, we observed a marked clinical improvement not only in the patient's sleep quality but also in their neurological outcomes. While coenzyme Q10 was part of this combination therapy, its specific contribution to alleviating sleep apnea symptoms cannot be isolated from the other treatments. Overall, the findings suggest that recognizing and treating sleep apnea promptly can enhance patients’ well-being and potentially improve neurological conditions associated with Leigh disease.
An overnight sleep study revealed the presence of OSA, which had developed shortly before the neurological symptoms became apparent. Treatment included high doses of thiamine, coenzyme Q, L-carnitine, and vitamins C and E, along with effective management of OSA through continuous positive airway pressure (CPAP).
Following this combined approach, we observed a marked clinical improvement not only in the patient's sleep quality but also in their neurological outcomes. While coenzyme Q10 was part of this combination therapy, its specific contribution to alleviating sleep apnea symptoms cannot be isolated from the other treatments. Overall, the findings suggest that recognizing and treating sleep apnea promptly can enhance patients’ well-being and potentially improve neurological conditions associated with Leigh disease.
Read More
Most Useful Reviews
7.5
Memory and anxiety benefits
A wonderful complex for improving memory; my sleep has significantly enhanced and my anxiety has faded. I would recommend it wholeheartedly!
Read More
9
Restored sleep patterns
1 people found this helpful
This product has greatly boosted my energy. Previously, I felt unrefreshed even after excessive sleep. However, since taking 100 mg of CoQ10, I now sleep well and wake feeling revitalised, without needing daytime naps. This brand offers excellent value for money.
Read More
9
Boosts energy effectively
Great product, with no issues regarding aftertaste or acid reflux. It boosts energy and aids deep sleep, which I would highly recommend.
Read More
Medical Researches
SCIENTIFIC SCORE
Likely Ineffective
Based on 2 Researches
4.8
- All Researches
9.5
Coenzyme Q10 in sleep apnea study
We explored the impact of various treatments, including coenzyme Q10, on obstructive sleep apnea (OSA) in a patient with adult-onset Leigh disease. This condition often presents with severe neurological symptoms, complicating the patients’ overall health and quality of life.
An overnight sleep study revealed the presence of OSA, which had developed shortly before the neurological symptoms became apparent. Treatment included high doses of thiamine, coenzyme Q, L-carnitine, and vitamins C and E, along with effective management of OSA through continuous positive airway pressure (CPAP).
Following this combined approach, we observed a marked clinical improvement not only in the patient's sleep quality but also in their neurological outcomes. While coenzyme Q10 was part of this combination therapy, its specific contribution to alleviating sleep apnea symptoms cannot be isolated from the other treatments. Overall, the findings suggest that recognizing and treating sleep apnea promptly can enhance patients’ well-being and potentially improve neurological conditions associated with Leigh disease.
An overnight sleep study revealed the presence of OSA, which had developed shortly before the neurological symptoms became apparent. Treatment included high doses of thiamine, coenzyme Q, L-carnitine, and vitamins C and E, along with effective management of OSA through continuous positive airway pressure (CPAP).
Following this combined approach, we observed a marked clinical improvement not only in the patient's sleep quality but also in their neurological outcomes. While coenzyme Q10 was part of this combination therapy, its specific contribution to alleviating sleep apnea symptoms cannot be isolated from the other treatments. Overall, the findings suggest that recognizing and treating sleep apnea promptly can enhance patients’ well-being and potentially improve neurological conditions associated with Leigh disease.
Read More
0
CoQ10 ineffective for mitochondrial sleep apnea
We examined a rare case of mitochondrial encephalomyopathy featuring multiple complications including sleep apnea, cerebellar ataxia, and peripheral neuropathy—a combination never before documented in medical literature. The patient received six months of coenzyme Q10 therapy to address the underlying mitochondrial dysfunction.
Unfortunately, the treatment proved ineffective. Neither the cerebellar ataxia nor the abnormal pyruvate metabolism improved with CoQ10 supplementation. While sleep apnea was identified as a significant prognostic factor in this mitochondrial disorder, the supplement failed to alleviate this serious breathing complication or other associated symptoms.
Unfortunately, the treatment proved ineffective. Neither the cerebellar ataxia nor the abnormal pyruvate metabolism improved with CoQ10 supplementation. While sleep apnea was identified as a significant prognostic factor in this mitochondrial disorder, the supplement failed to alleviate this serious breathing complication or other associated symptoms.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 9 Reviews
7.9
- All Reviews
- Positive Reviews
- Negative Reviews
7.5
Memory and anxiety benefits
A wonderful complex for improving memory; my sleep has significantly enhanced and my anxiety has faded. I would recommend it wholeheartedly!
Read More
9
Restored sleep patterns
1 people found this helpful
This product has greatly boosted my energy. Previously, I felt unrefreshed even after excessive sleep. However, since taking 100 mg of CoQ10, I now sleep well and wake feeling revitalised, without needing daytime naps. This brand offers excellent value for money.
Read More
9
Boosts energy effectively
Great product, with no issues regarding aftertaste or acid reflux. It boosts energy and aids deep sleep, which I would highly recommend.
Read More
7.5
Youthful vitality noted
I started taking it for health and youthful preservation, and it seems effective. My sleep has improved significantly, allowing for a more active morning after taking one capsule each night before bed with ashwagandha.
Read More
7.5
Overall health boost
Taking this supplement has been a brilliant decision. I feel more energised, my digestion has improved, and my sleep quality has significantly increased. I would highly recommend it to anyone after a comprehensive health boost.
Read More
Frequently Asked Questions
7.5
Significant health improvements
93 people found this helpful
Excellent preparation. It genuinely helps and is worth the money. Being over 50, I regret not knowing about coenzyme Q10 earlier, as I learned it decreases with age. I first purchased it after discovering that it can slow the ageing process. After taking it for about a year—initially bought in Russia but now on iHerb, as it's almost half the price—I've experienced noticeable improvements: 1) my headaches have almost stopped, 2) my sleep has improved significantly, 3) my immunity feels stronger, likely due to the vitamin E in the capsules, 4) I have more energy, and 5) my heart concerns have diminished as coenzyme stimulates my heart's energy processes. I noticed these benefits over the last 5-6 months. Consistent daily intake is vital for the best effects.
9
Boosts energy effectively
Great product, with no issues regarding aftertaste or acid reflux. It boosts energy and aids deep sleep, which I would highly recommend.
7.5
Memory and anxiety benefits
A wonderful complex for improving memory; my sleep has significantly enhanced and my anxiety has faded. I would recommend it wholeheartedly!
9
Restored sleep patterns
1 people found this helpful
This product has greatly boosted my energy. Previously, I felt unrefreshed even after excessive sleep. However, since taking 100 mg of CoQ10, I now sleep well and wake feeling revitalised, without needing daytime naps. This brand offers excellent value for money.
7.5
Youthful vitality noted
I started taking it for health and youthful preservation, and it seems effective. My sleep has improved significantly, allowing for a more active morning after taking one capsule each night before bed with ashwagandha.
6
Mood and sleep improvement
I took this coenzyme alongside magnesium l-threonate, and I believe this combination positively affects my sleep and mood.
0
Sleep issues noted
After using it, I couldn't stay asleep. I felt jittery.
9.5
Coenzyme Q10 in sleep apnea study
We explored the impact of various treatments, including coenzyme Q10, on obstructive sleep apnea (OSA) in a patient with adult-onset Leigh disease. This condition often presents with severe neurological symptoms, complicating the patients’ overall health and quality of life.
An overnight sleep study revealed the presence of OSA, which had developed shortly before the neurological symptoms became apparent. Treatment included high doses of thiamine, coenzyme Q, L-carnitine, and vitamins C and E, along with effective management of OSA through continuous positive airway pressure (CPAP).
Following this combined approach, we observed a marked clinical improvement not only in the patient's sleep quality but also in their neurological outcomes. While coenzyme Q10 was part of this combination therapy, its specific contribution to alleviating sleep apnea symptoms cannot be isolated from the other treatments. Overall, the findings suggest that recognizing and treating sleep apnea promptly can enhance patients’ well-being and potentially improve neurological conditions associated with Leigh disease.
An overnight sleep study revealed the presence of OSA, which had developed shortly before the neurological symptoms became apparent. Treatment included high doses of thiamine, coenzyme Q, L-carnitine, and vitamins C and E, along with effective management of OSA through continuous positive airway pressure (CPAP).
Following this combined approach, we observed a marked clinical improvement not only in the patient's sleep quality but also in their neurological outcomes. While coenzyme Q10 was part of this combination therapy, its specific contribution to alleviating sleep apnea symptoms cannot be isolated from the other treatments. Overall, the findings suggest that recognizing and treating sleep apnea promptly can enhance patients’ well-being and potentially improve neurological conditions associated with Leigh disease.
References
- Tatsumi C, Takahashi M, Yorifuji S, Nishikawa Y, Kitaguchi M, et al. Mitochondrial encephalomyopathy with sleep apnea. Eur Neurol. 1988;28:64. PubMed
- Mermigkis C, Bouloukaki I, Mastorodemos V, Plaitakis A, Alogdianakis V, et al. Medical treatment with thiamine, coenzyme Q, vitamins E and C, and carnitine improved obstructive sleep apnea in an adult case of Leigh disease. Sleep Breath. 2013;17:1129. 10.1007/s11325-013-0816-5
